Taking the Guesswork out of HFpEF

With an aging population and a higher burden of comorbidities, the proportion of heart failure patients with a preserved ejection fraction, i.e. ejection fraction ≥ 50% is increasing.1 Heart failure with preserved ejection fraction (HFpEF) now accounts for more than half of all heart failure hospitalizations. Despite the increasing prevalence, HFpEF remains a nebulous entity. … Read more

New Treatment Options for Transthyretin Cardiac Amyloidosis – What do I need to know?

Clinical Features and Pathophysiology of Transthyretin Cardiac Amyloidosis (TTR-CA) There has been an increasing awareness of the presence of cardiac amyloidosis (CA) in patients presenting with heart failure with preserved left ventricular ejection fraction (HFpEF). The clinical features suggestive of CA are recurrent heart failure with preserved ejection fraction (HFpEF) and restrictive left ventricular filling … Read more