Inflammation: A Hallmark of Abdominal Aortic Aneurysm Pathophysiology

In my previous blog post, I discussed the animal models used for studying abdominal aortic aneurysms (AAAs), the progressive dilation of the aorta which if left untreated, will lead to fatal aortic rupture. Currently, there are no pharmacological treatments available for this devastating condition and the current clinical approach is to monitor the aortic dimension … Read more

Abdominal Aortic Aneurysm: How to Study It in Mice

Aortic aneurysms are pathological dilations with high risk of mortality due to rupture. Abdominal aortic aneurysms (AAA) are the most common form of this condition with the dilation being mainly present in the infrarenal region. Histological analysis of human AAA tissue have shed lights on pathological hallmarks of AAAs, however, such tissues are acquired at … Read more