pharmacological

Pharmacological Smoking Cessation Aides And Cardiovascular Safety

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Pharmacological smoking cessation therapies have had their challenges. For example, varenicline previously had a US Food and Drug Administration black box warning regarding neuropsychiatric risks. The EAGLES study, published 2016, was an industry sponsored, randomized, placebo-controlled trial of nicotine, varenicline, and bupropion that sought to address the neuropsychiatric risk profile of these medications.1 They randomized … Read more

It’s Electric!

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As this crowd knows, cardiovascular disease is the leading cause of death worldwide, and though we’ve made great advancements to reduce morbidity and mortality in these patients, there is a desperate search for innovative new treatment strategies.   Traditionally, most chronic conditions are addressed with small molecule-based drugs that bind to their molecular target, exert … Read more