A different kind of extended window for stroke treatment

To fanfare at International Stroke Conference 2018, the results of the DEFUSE 31 extended window thrombectomy study were announced. The American Heart Association/American Stroke Association acute ischemic stroke guidelines were immediately updated to reflect the practice-changing findings.  A few months later, Lee Schwamm and colleagues published their findings from MR WITNESS.2 In this study, patients … Read more

Parsing The Updated 2018 Acute Ischemic Stroke Guidelines: Smoking Cessation

The 2018 International Stroke Conference was headlined by the practice-changing results of DEFUSE 3 and related acute stroke care guideline updates. Having returned to our institutions, neurologists are parsing the updated 2018 acute ischemic stroke guidelines1 and wondering how best to operationalize the latest data.   Overshadowed by updated guidelines regarding the extended window and … Read more

An Early Career Perspective On International Stroke Conference 2018

I have come to look forward to the annual International Stroke Conference each year. Due to the largess of my mentors and support of my residency program, I have had the good fortune of attending the conference each year since my third year of residency. As a third-year resident, I had decided to pursue fellowship … Read more

DEFUSE 3 Definitively Expands The Endovascular Therapy Window

Writing from the 2018 International Stroke Conference, it is difficult to report on anything other than the game-changing results of DEFUSE 3. After years of clinical suspicion that endovascular therapy works, definitive evidence establishing the role of endovascular therapy in acute stroke care was first presented at the International Stroke Conference in 2015. Since then, … Read more

Stroke Advances In 2017: An Overview, Reflections, And A Call To Action

2017 gave us numerous dramatic advances in stroke neurology. We were treated to compelling data regarding the favorability of patent foramen ovale closure in well-selected individuals with cryptogenic stroke.1,2,3 Endovascular therapy matured with the extension of the treatment time window.4 We even saw promising rehabilitation data regarding surgical nerve transfer for chronic spastic arm paralysis.5 … Read more