Atherosclerotic cardiovascular disease (ASCVD) is the number one cause of death in the Western world.[1] Since 2016, cardiovascular diseases have caused 1 in 3 deaths in the United States, and this trend is expected to continue in the future. There is a well-established relationship between ASCVD and elevated levels of low-density lipoprotein C (LDL-C), often … Read more
Pathophysiology of a classic acute MI is attributed to the concept of coronary atherothrombosis leading to myocardial ischaemia and ultimately infarction. The overall prognostic benefit with coronary revascularization has been established in these patients. Recently, there is a significant research and clinical interest in acute MI presentations without evidence of significant atherothromotic lesions, so that … Read more
One of the highly anticipated stories for Scientific Sessions 2018 was the new lipid guidelines. Following the reactions on Twitter during the session, I read a lot of opinions on CAC scoring and the pros and cons of its use to further stratify those at intermediate risk. Also trending – when to target LDL-C, now … Read more